Hereditary kidney cancer is estimated to constitute 3-5% of all kidney cancers. For details on hereditary kidney cancers, see the Other Hereditary Kidney Cancer Syndromes section.
Non-hereditary RCC is called sporadic. Sporadic kidney cancer can also be of the clear cell, papillary or chromophobe types—these three make up 85-90% of all kidney cancers. Other types include medullary, translocation, transitional cell, and collecting duct cancers, as well as cancers that have sarcomatoid features. The cancer may also be unclassified or mixed. Sporadic kidney cancer occurs because of a sporadic mutation and may possibly be related to obesity, smoking, high blood pressure or exposure to certain chemicals.
Publication date: September 2012
Review date: September 2015