Folliculin Signalling Diagram

Last reviewed – May 2013

Singh et al., 2006
Baba et al., 2006
Baba et al., 2008
Hasumi et al., 2008
Dephoure et al., 2008
Takagi et al., 2008
Chen et al., 2008
Komori et al., 2009
Hartman et al., 2009
Gauci et al., 2009
Hasumi et al., 2009
Piao et al., 2009
Wang et al., 2010
Hudon et al., 2010
Hong et al., 2010a
Behrends et al., 2010
Klomp et al., 2010
Hong et al., 2010b
Preston et al., 2011
Danielsen et al., 2011
Cash et al., 2011
Yu et al., 2011
Peña-Llopis et al., 2011
Wagner et al., 2011
Dodding et al., 2011
Lim et al., 2012
Furuya et al., 2012
Park et al., 2012
Baba et al., 2012
Nookala et al., 2012
Nahorski et al., 2012
Gaur et al., 2012
Medvetz et al., 2012
Hasumi et al., 2012
Reiman et al., 2012
Sano et al., 2012
Pimenta et al., 2012
Nishii et al., 2012
Pradella et al., 2013
Lu et al., 2013
Kawaii et al., 2013
Gharbi et al., 2013

The interactive diagram above illustrates the relationship between Folliculin (FLCN) and a number of proteins and signalling pathways, which are discussed in more detail below. In particular, the diagram highlights those factors that are currently thought to be directly linked to FLCN, while related pathways which provide context for these associations are faded.

Please click on each protein or pathway for more information. To view the pop-up boxes, click ‘Expand’ to see 1) the post-translational modifications associated with FLCN and 2) its C-terminal structure and interactome .

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