Comments on: BHD and Tuberous sclerosis (TSC) – Part I: Overview

By: Degradation of HIF-1α by Hypericin | BHD Research

Degradation of HIF-1α by Hypericin | BHD Research — Mon, 21 Nov 2011 14:53:11 +0000

[...] and metabolism, and it has been implicated in tumour growth in several disorders such as VHL and TSC. Preston et al. (2010) demonstrated that HIF-1α activity was increased in FLCN-null cells and that [...]

By: Degradation of HIF-1α by Hypericin | Birt-Hogg-Dubé Syndrome

Degradation of HIF-1α by Hypericin | Birt-Hogg-Dubé Syndrome — Mon, 21 Nov 2011 14:44:29 +0000

By: Tuberous sclerosis complex and autophagy | BHD Research

Tuberous sclerosis complex and autophagy | BHD Research — Fri, 16 Sep 2011 14:07:59 +0000

[...] Given the clinical similarities between TSC and BHD syndrome (which have been discussed in a previous blog), could autophagy play a role in BHD-associated tumourigenesis and be a novel therapeutic target? [...]

By: Tuberous sclerosis complex and autophagy | Birt-Hogg-Dubé Syndrome

Tuberous sclerosis complex and autophagy | Birt-Hogg-Dubé Syndrome — Fri, 16 Sep 2011 14:03:24 +0000

By: Lab-profile: Dr Andrew Tee – Cardiff University, UK | BHD Research

Lab-profile: Dr Andrew Tee – Cardiff University, UK | BHD Research — Tue, 12 Jul 2011 22:44:34 +0000

[...] discussed in a previous blog, the clinical similarities between BHD syndrome and TSC suggest that FLCN and the TSC proteins may [...]

By: Lab-profile: Dr Andrew Tee – Cardiff University, UK | Birt-Hogg-Dubé Syndrome

Fri, 17 Jun 2011 10:36:45 +0000

[...] discussed in a previous blog, the clinical similarities between BHD syndrome and TSC suggest that FLCN and the TSC proteins may [...]

By: HIF signalling joins the BHD network « Birt-Hogg-Dubé Syndrome

HIF signalling joins the BHD network « Birt-Hogg-Dubé Syndrome — Fri, 17 Dec 2010 14:21:22 +0000

[...] posts, BHD syndrome shares some phenotypic similarities with other rare diseases, such as HLRCC, TSC and VHL disease. Hypoxia-inducible factor (HIF) controls processes such as cell proliferation and [...]