BHD Literature Database Updated

The BHD Literature Database has been updated with a pathological study of BHD-associated pulmonary cysts in 11 individuals from 9 families.

The researchers found that the inner walls of BHD-associated cysts are lined with epithelial cells, and that many of the cysts exhibited internal septa or alveoli within an alveolus. Additionally, positive staining for phospho-S6 ribosomal protein expression pointed to activation of the mTOR pathway. The authors concluded by suggesting that BHD-associated cysts may be considered hamartoma-like cystic alveolar formations associated with disregulated mTOR signalling.

To find out more, download the latest version of the database here.

Unlike
This entry was posted in News. Bookmark the permalink.

Leave a Reply

Your email address will not be published. Required fields are marked *

*

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>