The application of Proteomics to BHD research?

Genomic and clinical studies make up the majority of published research into BHD Syndrome. Proteomics is the large scale analysis of proteins (or the ‘proteome’) and can be used to identify differential transcription of proteins and their biological activity. There are currently no proteomic based studies being performed in the field of BHD research.Would its implementation help further our knowledge of the disease and support ongoing studies? A Chinese group based at the Beijing Proteome Research Centre, China have used proteomic analysis to provide comprehensive functional annotation of proteins implicated in liver development and disease (Sun et al, 2010), could a similar project be used to identify the ins and outs of the BHD kidney?

Sun A et al, 2010. Liverbase: a comprehensive view of human liver biology. J Proteome Res. Jan;9(1):50-8.

Leave a Reply

Your email address will not be published. Required fields are marked *